PREVALENCE AND ANTIMICROBIAL RESISTANCE OF ESCHERICHIA COLI ISOLATES FROM URINARY TRACT INFECTIONS IN PEDIATRIC PATIENTS: AN INTEGRATIVE LITERATURE REVIEW (2015–2025)
DOI:
https://doi.org/10.54578/unesc.v10i1.574Abstract
Urinary tract infections (UTIs) are among the most common causes of bacterial infections in the pediatric population, with Escherichia coli being responsible for more than 80% of pyelonephritis cases. There is a global trend of increasing resistance to commonly used antibiotics for the treatment of these UTIs, as well as ESBL-producing strains and multidrug resistance (MDR). Therefore, this study presented an integrative review whose objective was to critically analyze all available evidence on the prevalence and antimicrobial resistance of E. coli isolated in urinary tract infections in pediatric patients between 2015 and 2025. The results confirmed the bacterium as the main etiological agent of pediatric UTIs in various regions of the world, in addition to increasing trends of resistance to ampicillin, amoxicillin-clavulanate, and third-generation cephalosporins, and, conversely, good sensitivity rates to nitrofurantoin and fosfomycin. Therefore, there is an urgent need to review pharmacotherapies, as well as to provide continuing education on the rational use of antimicrobials.
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2026 UNESC Journal

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.









